Her professional music career began singing lead for an R&B group called The Boys Next Door. The group signed with Jermaine Jackson's label Work Records, which later folded. Tyler eventually signed with RCA Records and released her debut album Girls Nite Out. She co-wrote the lead single "Whatcha Gonna Do" which peaked at #3 on the Billboard R&B chart. The 1990 follow-up single "Girls Nite Out" topped out at #6 on the Billboard's R&B charts, as well as #6 on its Pop charts.
Collins songwriting came to the forefront for her second album Tyler, which was a decidedly more pop-oriented effort than Girls Nite Out. The set featured standout the singles "It Doesn't Matter" (co-written by Siedah Garrett) and "Just Make Me The One". Tyler has also written songs for Celine Dion, Shanice, and Jeffrey Osborne.
Her work with Prince lead to a solo recording contract at Warner Bros. Records. Though a full length release never materialized, the deal did yield Collins' recording of the Top 20 Adult Contemporary song "Thanks to You", the theme song to the Paramount Pictures' film Andre. A music video for the song is included at the end of the movie.
Apart from her singing career, Collins has also appeared in several television shows and motion pictures. She played the role of Tina in the 1991 film A Rage in Harlem, starring Gregory Hines and Forest Whitaker. She also starred in another film entitled Why Colors? and played her highest-profile role as Cinderella on an episode of The Fresh Prince of Bel-Air